The Things We Do – Dr. Halstead rushes to rescue Dr. Manning after she is involved in a Medevac helicopter crash. The personal drama between Dr. Rhodes and Dr. Bekker boils over. Dr. Charles and Dr. Choi work to help a patient come to terms with their addiction. April helps Elsa deal with the loss of her first patient.
Who Can You Trust – Will adjusts to hospital life in the aftermath of his recent undercover activities. Ethan and April’s personal relationship starts to interfere with their working situation. Dr. Charles and Dr. Manning collaborate on a patient suffering from Alzheimer’s. Dr. Rhodes and Dr. Bekker have a difference of opinion in dealing with a woman in desperate need of a kidney transplant
All the Lonely People – April finds herself in a dangerous situation and Natalie gets an update on Will. Dr. Rhodes gears up for a gala honoring his hybrid O.R. and tries to convince Dr. Bekker to join him
Death Do Us Part – Will and Natalie prepare for their big day, but Will soon finds himself sidetracked. Dr. Charles disagrees with Goodwin on how to best handle a patient’s treatment while Dr. Choi and April are on their own when a pregnant woman delivers. Dr. Rhodes finds himself operating on a patient that is of great importance to Det. Halstead.
Play By My Rules – Dr. Charles struggles to convince Dr. Choi that surgery isn’t always the answer. Dr. Rhodes finds himself in hot water with Goodwin when he disobeys her direct order. April becomes frustrated with Maggie when she continues to question her leadership role as the stand-in charge nurse. Dr. Manning suspects Dr. Halstead is keeping something from her.
The Poison Inside Us – The hospital is forced to evacuate when a toxic chemical is brought into the E.D., leaving patients and the staff in grave danger. Stuck in an elevator, Dr. Charles and Dr. Manning are forced to take drastic measures with a pregnant woman. Goodwin is tasked with making difficult choices and Dr. Rhodes discovers a secret that Dr. Bekker has been holding from him.
Lesser of Two Evils – Dr. Manning and Dr. Halstead become skeptical of a patient’s injuries when the victim of a car accident is brought into the hospital. Ethan and April have a difficult time understanding Emily’s attachment to her boyfriend despite recent developments. Will and Natalie brace for their joint bachelor/bachelorette party.
What You Don’t Know – When things become complicated, Will is forced to lie to Natalie. Ethan and April find out some compromising information about Emily’s boyfriend and Ava is unsure of what to do with a patient who is refusing treatment.
Backed Against the Wall – Dr. Halstead gets an unplanned visit from the CPD; Ethan is skeptical of a woman who is experiencing chronic pain; Natalie tends to a cancer patient whose brother has strong feelings on why he is refusing to lend his assistance.
Heavy Is the Head – When a sick boy is brought in, Ethan is faced with a tough decision that quickly escalates into a complicated and dangerous situation. Connor and Maggie are put to the test, while Natalie and Ethan aren’t sure what to make of Elsa, the new third-year medical student.