Peace of Mind – Sam and Castiel follow a case to a picturesque little town in Arkansas, only to find out nothing is as idyllic as it appears to be. Dean and Jack take a road trip to visit an old friend.
Ouroboros – Sam and Dean enlist the help of Rowena to track down a demi god who feasts on human flesh. The challenge of keeping Michael at bay is proving to be more difficult than originally anticipated.
Lebanon – Sam and Dean look to occult lore for a solution to their latest problem, but instead of a resolution, they find much more than either of them had anticipated.
Prophet and Loss – Sam and Dean must figure out how to stop the bloodshed when Donatello, who, in his current condition, is inadvertently scrambling the order of future prophets. Nick comes face-to-face with his past.
Damaged Goods – Dean spends some bonding time with Mary and Donna. Nick finally finds the answer he has been searching for. Sam is left to make an unimaginable choice.
Nihilism – Michael has re-taken control of Dean as his army of monsters continues to move in on the heroes. Sam devises a plan to try and reach Dean and stop Michael before anyone else has to die.
The Spear – Sam and Dean enlist the help of their pal Garth to gain inside information on what Michael may be planning. The brothers split up to each go after weapons that can aid in their fight against the Archangel, but this may be a fight our heroes cannot win.
Byzantium – Sam and Dean join forces with an unexpected ally, and the outcome will alter the course of two lives. Meanwhile, Heaven faces an attack from a dark force, driving Castiel to make an enormous sacrifice to make things right.
Unhuman Nature – Sam and Castiel track down a Shaman who may be able to help a friend. Nick continues to spiral down a dark path as he looks for answers surrounding the deaths of his wife and son. Jack turns to Dean for help enjoying the human experience.
Optimism – Sam and Charlie team up to get to the bottom of a string of random disappearances. Meanwhile, Jack believes that he has found a case and convinces Dean to partner with him on the hunt.